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KMID : 0383820090670030244
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Tuberculosis and Respiratory Diseases
2009 Volume.67 No. 3 p.244 ~ p.248
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A Case of Extramedullary Hematopoiesis Presenting as a Lung Mass in a Patient with Primary Myelofibrosis
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Kim Yeo-Myeong
Kim Hyeon-Tae
Noh Geum-Yeub
Kang Min-Soo
Chang Yoon-Hwan
Kim Hye-Ryoun
Lee Jae-Cheol
Kim Cheol-Hyeon
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Abstract
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Primary myelofibrosis is characterized by replacement of bone marrow with fibrotic tissue and the development of extramedullary hematopoiesis. Extramedullary hematopoiesis primarily involves the spleen and liver, but can also occur in the lungs. We report the case of an 80-year-old male who was admitted for evaluation of a lung mass and persistent thrombocytopenia. A percutaneous needle aspiration from the mass in the right lower lung showed myelopoietic cells with fatty tissue. A bone marrow biopsy revealed a hypercellular marrow with an increased number of atypical megakaryocytes. The final diagnosis was a prefibrotic stage of primary myelofibrosis leading to extramedullary hematopoiesis in the lung.
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KEYWORD
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Extramedullary hematopoiesis, Primary myelofibrosis, Lung mass
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